Version 5.4
Homo sapiens Protein: STX10
Summary
InnateDB Protein IDBP-31907.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX10
Protein Name syntaxin 10
Synonyms hsyn10; SYN10;
Species Homo sapiens
Ensembl Protein ENSP00000339350
InnateDB Gene IDBG-31903 (STX10)
Protein Structure
UniProt Annotation
Function SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. {ECO:0000269PubMed:18195106}.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed at high levels in heart, skeletal muscle and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006906 vesicle fusion
GO:0016192 vesicle-mediated transport
GO:0042147 retrograde transport, endosome to Golgi
GO:0048193 Golgi vesicle transport
Cellular Component
GO:0000139 Golgi membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
IPR010989 t-SNARE
IPR015260 Syntaxin 6, N-terminal
PFAM PF05739
PF09177
PRINTS
PIRSF
SMART SM00397
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60499
PhosphoSite PhosphoSite-O60499
TrEMBL
UniProt Splice Variant
Entrez Gene 8677
UniGene
RefSeq NP_001258540
HUGO HGNC:11428
OMIM 603765
CCDS CCDS62571
HPRD 04791
IMGT
EMBL AC011446 AF035531 BC017237 CR457110
GenPept AAC05087 AAH17237 CAG33391

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca