InnateDB Protein
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IDBP-32026.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BCDIN3D
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Protein Name
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BCDIN3 domain containing
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000335201
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InnateDB Gene
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IDBG-32024 (BCDIN3D)
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Protein Structure
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Function |
O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs. {ECO:0000269PubMed:23063121}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:23063121}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR010675
Bicoid-interacting 3
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
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PFAM |
PF06859
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7Z5W3
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PhosphoSite |
PhosphoSite-Q7Z5W3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
144233
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UniGene |
Hs.142736
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RefSeq |
NP_859059
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HUGO |
HGNC:27050
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OMIM |
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CCDS |
CCDS8790
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HPRD |
14065
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IMGT |
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EMBL |
AK292194
BC053560
CH471111
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GenPept |
AAH53560
BAF84883
EAW58101
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