InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MT1G

Summary

InnateDB Protein

IDBP-32360.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MT1G

Protein Name

metallothionein 1G

Synonyms

MT1; MT1K;

Species

Homo sapiens

Ensembl Protein

ENSP00000369139

InnateDB Gene

IDBG-32358 (MT1G)

Protein Structure

UniProt Annotation

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	3 [view]
Protein-DNA	10 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0030224	monocyte differentiation
GO:0035924	cellular response to vascular endothelial growth factor stimulus
GO:0042117	monocyte activation
GO:0045926	negative regulation of growth
GO:0071276	cellular response to cadmium ion
GO:0071280	cellular response to copper ion
GO:0071294	cellular response to zinc ion