Version 5.4
Homo sapiens Protein: EMC2
Summary
InnateDB Protein IDBP-32435.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EMC2
Protein Name tetratricopeptide repeat domain 35
Synonyms KIAA0103; TTC35;
Species Homo sapiens
Ensembl Protein ENSP00000220853
InnateDB Gene IDBG-32433 (EMC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269PubMed:22119785}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0072546 ER membrane protein complex
Protein Structure and Domains
PDB ID
InterPro IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15006
PhosphoSite PhosphoSite-Q15006
TrEMBL
UniProt Splice Variant
Entrez Gene 9694
UniGene Hs.654351
RefSeq NP_055488
HUGO HGNC:28963
OMIM 607722
CCDS CCDS6309
HPRD 09657
IMGT
EMBL BC020753 BC021667 CR457402 D14659
GenPept AAH20753 AAH21667 BAA03493 CAG33683

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca