Homo sapiens Protein: FBXW12 | |||||
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Summary | |||||
InnateDB Protein | IDBP-32448.6 | ||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
Gene Symbol | FBXW12 | ||||
Protein Name | F-box and WD repeat domain containing 12 | ||||
Synonyms | |||||
Species | Homo sapiens | ||||
Ensembl Protein | ENSP00000296438 | ||||
InnateDB Gene | IDBG-32446 (FBXW12) | ||||
Protein Structure |
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UniProt Annotation | |||||
Function | Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. {ECO:0000250}. | ||||
Subcellular Localization | |||||
Disease Associations | |||||
Tissue Specificity | Ubiquitously expressed. {ECO:0000269PubMed:15040455}. | ||||
Comments | |||||
Interactions | |||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||
PDB ID | |||||
InterPro |
IPR001810
F-box domain IPR011044 Quinoprotein amine dehydrogenase, beta chain-like |
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PFAM |
PF00646
PF12937 PF13013 |
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PRINTS | |||||
PIRSF | |||||
SMART |
SM00256
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TIGRFAMs | |||||
Post-translational Modifications | |||||
Modification | |||||
Cross-References | |||||
SwissProt | Q6X9E4 | ||||
PhosphoSite | PhosphoSite-Q6X9E4 | ||||
TrEMBL | C9JK86 | ||||
UniProt Splice Variant | |||||
Entrez Gene | 285231 | ||||
UniGene | Hs.288793 | ||||
RefSeq | NP_996985 | ||||
HUGO | HGNC:20729 | ||||
OMIM | 609075 | ||||
CCDS | CCDS2764 | ||||
HPRD | 16428 | ||||
IMGT | |||||
EMBL | AC104448 AY247969 BC101304 BC101305 | ||||
GenPept | AAI01305 AAI01306 AAP75562 | ||||