Version 5.4
Homo sapiens Protein: CETN3
Summary
InnateDB Protein IDBP-33119.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CETN3
Protein Name centrin, EF-hand protein, 3
Synonyms CDC31; CEN3;
Species Homo sapiens
Ensembl Protein ENSP00000283122
InnateDB Gene IDBG-33117 (CETN3)
Protein Structure
UniProt Annotation
Function Plays a fundamental role in microtubule-organizing center structure and function.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Centrosome of interphase and mitotic cells.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0007098 centrosome cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0045111 intermediate filament cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15182
PhosphoSite PhosphoSite-O15182
TrEMBL H0YBL5
UniProt Splice Variant
Entrez Gene 1070
UniGene Hs.128073
RefSeq NP_004356
HUGO HGNC:1868
OMIM 602907
CCDS CCDS4066
HPRD 04216
IMGT
EMBL AC093510 BC005383 BC093793 BC112040 BT006688 Y12473
GenPept AAH05383 AAH93793 AAI12041 AAP35334 CAA73077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca