InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDX39A

Summary

InnateDB Protein

IDBP-33232.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX39A

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A

Synonyms

BAT1; BAT1L; DDX39; DDXL; URH49;

Species

Homo sapiens

Ensembl Protein

ENSP00000322749

InnateDB Gene

IDBG-33228 (DDX39A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.

Experimentally validated
Total	44 [view]
Protein-Protein	44 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006406	mRNA export from nucleus

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00270

PRINTS

PIRSF

SMART

SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O00148