Version 5.4
Homo sapiens Protein: GPR114
Summary
InnateDB Protein IDBP-33441.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR114
Protein Name G protein-coupled receptor 114
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000342981
InnateDB Gene IDBG-33439 (GPR114)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000203 GPS motif
IPR000832 GPCR, family 2, secretin-like
IPR003910 GPCR, family 2, orphan receptor, GPR56
IPR017981 GPCR, family 2-like
PFAM PF01825
PF00002
PRINTS PR00249
PR01422
PIRSF
SMART SM00303
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IZF4
PhosphoSite PhosphoSite-Q8IZF4
TrEMBL A0A024R6S3
UniProt Splice Variant
Entrez Gene 221188
UniGene Hs.609254
RefSeq NP_722579
HUGO HGNC:19010
OMIM
CCDS CCDS10785
HPRD 17056
IMGT
EMBL AK128298 AK160368 AK172765 AY140956 AY255609 AY358447 BC032401 CH471092
GenPept AAH32401 AAN46670 AAO85121 AAQ88812 BAD18711 BAD18748 BAG54657 EAW82936 EAW82938

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca