Homo sapiens Protein: ARL11 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Protein | IDBP-33689.5 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | ARL11 | ||||||||||||||||||
Protein Name | ADP-ribosylation factor-like 11 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Protein | ENSP00000282026 | ||||||||||||||||||
InnateDB Gene | IDBG-33687 (ARL11) | ||||||||||||||||||
Protein Structure | |||||||||||||||||||
UniProt Annotation | |||||||||||||||||||
Function | May play a role in apoptosis. May act as a tumor suppressor. {ECO:0000269PubMed:15843669}. | ||||||||||||||||||
Subcellular Localization | |||||||||||||||||||
Disease Associations | Leukemia, chronic lymphocytic (CLL) [MIM:151400]: A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||||||||||||||||||
Tissue Specificity | Expressed in lung and leukocytes. {ECO:0000269PubMed:15843669}. | ||||||||||||||||||
Comments | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||||||||
PDB ID | |||||||||||||||||||
InterPro |
IPR001806
Small GTPase superfamily IPR005225 Small GTP-binding protein domain IPR006687 Small GTPase superfamily, SAR1-type IPR006689 Small GTPase superfamily, ARF/SAR type IPR006762 Gtr1/RagA G protein IPR013684 Mitochondrial Rho-like IPR019009 Signal recognition particle receptor, beta subunit IPR024156 Small GTPase superfamily, ARF type IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF00071
PF00025 PF04670 PF08477 PF09439 |
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PRINTS |
PR00449
PR00328 |
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PIRSF | |||||||||||||||||||
SMART |
SM00178
SM00177 |
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TIGRFAMs | |||||||||||||||||||
Post-translational Modifications | |||||||||||||||||||
Modification | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | Q969Q4 | ||||||||||||||||||
PhosphoSite | PhosphoSite-Q969Q4 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 115761 | ||||||||||||||||||
UniGene | Hs.558599 | ||||||||||||||||||
RefSeq | NP_612459 | ||||||||||||||||||
HUGO | HGNC:24046 | ||||||||||||||||||
OMIM | 609351 | ||||||||||||||||||
CCDS | CCDS9419 | ||||||||||||||||||
HPRD | 12484 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AF441378 AK091249 AL135901 BC013150 | ||||||||||||||||||
GenPept | AAH13150 AAP19650 BAC03621 CAI40715 | ||||||||||||||||||