InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRKAR2A

Summary

InnateDB Protein

IDBP-33723.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRKAR2A

Protein Name

protein kinase, cAMP-dependent, regulatory, type II, alpha

Synonyms

PKR2; PRKAR2;

Species

Homo sapiens

Ensembl Protein

ENSP00000296446

InnateDB Gene

IDBG-33721 (PRKAR2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	56 [view]
Protein-Protein	55 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008603	cAMP-dependent protein kinase regulator activity
GO:0016301	kinase activity

Biological Process

GO:0001932	regulation of protein phosphorylation
GO:0016310	phosphorylation
GO:0045859	regulation of protein kinase activity

Cellular Component

GO:0005952

cAMP-dependent protein kinase complex

Protein Structure and Domains

PDB ID

InterPro

IPR000595 Cyclic nucleotide-binding domain
IPR002373 cAMP/cGMP-dependent protein kinase
IPR003117 Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit
IPR012198 cAMP-dependent protein kinase regulatory subunit
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF00027
PF02197

PRINTS

PR00103

PIRSF

PIRSF000548

SMART

SM00100
SM00394

TIGRFAMs

Post-translational Modifications

Modification

Cross-References