InnateDB Protein
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IDBP-3406.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HSCB
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Protein Name
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HscB iron-sulfur cluster co-chaperone homolog (E. coli)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000216027
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InnateDB Gene
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IDBG-3404 (HSCB)
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Protein Structure
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Function |
Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. {ECO:0000269PubMed:20668094}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:20668094}. Mitochondrion {ECO:0000269PubMed:20668094}.
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Disease Associations |
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Tissue Specificity |
Expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart. {ECO:0000269PubMed:12938016, ECO:0000269PubMed:20668094}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001623
DnaJ domain
IPR004640
Co-chaperone Hsc20
IPR009073
Co-chaperone HscB, C-terminal oligomerisation domain
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PFAM |
PF00226
PF07743
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PRINTS |
PR00625
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PIRSF |
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SMART |
SM00271
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TIGRFAMs |
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Modification |
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SwissProt |
Q8IWL3
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PhosphoSite |
PhosphoSite-Q8IWL3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
150274
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UniGene |
Hs.632780
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RefSeq |
NP_741999
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HUGO |
HGNC:28913
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OMIM |
608142
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CCDS |
CCDS13845
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HPRD |
16289
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IMGT |
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EMBL |
AL023494
AL117330
AY191719
BC065569
CR456462
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GenPept |
AAH65569
AAN85282
CAG30348
CAH73876
CAI20339
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