Version 5.4
| Homo sapiens Protein: LRIT3 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-34067.7 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | LRIT3 | ||||
| Protein Name | leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Protein | ENSP00000328222 | ||||
| InnateDB Gene | IDBG-34065 (LRIT3) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs. {ECO:0000269PubMed:22673519}. | ||||
| Subcellular Localization | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. | ||||
| Disease Associations | Night blindness, congenital stationary, 1F (CSNB1F) [MIM:615058]: An autosomal recessive form of congenital stationary night blindness, a non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. {ECO:0000269PubMed:23246293}. Note=The disease is caused by mutations affecting the gene represented in this entry. | ||||
| Tissue Specificity | |||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR003961 Fibronectin, type III IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set |
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| PFAM |
PF00041
PF01108 PF07679 |
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| PRINTS | |||||
| PIRSF | |||||
| SMART |
SM00408
SM00409 SM00060 |
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | |||||
| PhosphoSite | PhosphoSite-Q3SXY7 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 345193 | ||||
| UniGene | Hs.308127 | ||||
| RefSeq | XP_005263036 | ||||
| HUGO | HGNC:24783 | ||||
| OMIM | 615004 | ||||
| CCDS | |||||
| HPRD | 13495 | ||||
| IMGT | |||||
| EMBL | |||||
| GenPept | |||||