Version 5.4
Homo sapiens Protein: GINS3
Summary
InnateDB Protein IDBP-34267.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GINS3
Protein Name GINS complex subunit 3 (Psf3 homolog)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000327449
InnateDB Gene IDBG-34261 (GINS3)
Protein Structure
UniProt Annotation
Function The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. {ECO:0000269PubMed:17417653}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BRX5
PhosphoSite PhosphoSite-Q9BRX5
TrEMBL
UniProt Splice Variant
Entrez Gene 64785
UniGene Hs.47125
RefSeq NP_001119602
HUGO HGNC:25851
OMIM 610610
CCDS CCDS45499
HPRD 07842
IMGT
EMBL AC009107 AC009118 AC084063 AK023974 AK315622 BC005879 BC014437 CH471092 CR457283
GenPept AAH05879 AAH14437 BAB14747 BAG37990 CAG33564 EAW82973 EAW82976

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca