Version 5.4
Homo sapiens Protein: KCNRG
Summary
InnateDB Protein IDBP-34351.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNRG
Protein Name potassium channel regulator
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000324191
InnateDB Gene IDBG-34349 (KCNRG)
Protein Structure
UniProt Annotation
Function Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. {ECO:0000269PubMed:12650944, ECO:0000269PubMed:19968958}.
Subcellular Localization Endoplasmic reticulum {ECO:0000269PubMed:19968958}.
Disease Associations
Tissue Specificity Ubiquitous in normal tissues and expressed in some tumor tissues. {ECO:0000269PubMed:12650944}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold
PFAM PF02214
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N5I3
PhosphoSite PhosphoSite-Q8N5I3
TrEMBL
UniProt Splice Variant
Entrez Gene 283518
UniGene Hs.660161
RefSeq NP_775876
HUGO HGNC:18893
OMIM 607947
CCDS CCDS9424
HPRD 06404
IMGT
EMBL AL137060 AY129653 AY129654 AY169387 AY169388 AY190921 AY190922 BC020887 BC032343 CH471075
GenPept AAH20887 AAH32343 AAN06090 AAN06091 AAO11777 AAO11778 AAO27464 AAO27465 CAM17621 CAM17622 EAX08849 EAX08850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca