Version 5.4
Homo sapiens Protein: RASAL3
Summary
InnateDB Protein IDBP-34725.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASAL3
Protein Name RAS protein activator like 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000341905
InnateDB Gene IDBG-34723 (RASAL3)
Protein Structure
UniProt Annotation
Function May function as a Ras GTPase-activating protein. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005099 Ras GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0032320 positive regulation of Ras GTPase activity
GO:0046580 negative regulation of Ras protein signal transduction
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR001936 Ras GTPase-activating protein
IPR008936 Rho GTPase activation protein
PFAM PF00168
PF00616
PRINTS PR00360
PIRSF
SMART SM00239
SM00323
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86YV0
PhosphoSite PhosphoSite-Q86YV0
TrEMBL V9GYD1
UniProt Splice Variant
Entrez Gene 64926
UniGene Hs.136979
RefSeq NP_075055
HUGO HGNC:26129
OMIM
CCDS CCDS46006
HPRD
IMGT
EMBL AC011492 AK025091 AK122587 BC030281
GenPept AAH30281 BAB15064 BAC56928

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca