Version 5.4
Homo sapiens Protein: MFAP4
Summary
InnateDB Protein IDBP-34761.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MFAP4
Protein Name microfibrillar-associated protein 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000299610
InnateDB Gene IDBG-34759 (MFAP4)
Protein Structure
UniProt Annotation
Function Could be involved in calcium-dependent cell adhesion or intercellular interactions.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0009650 UV protection
GO:0010712 regulation of collagen metabolic process
GO:0030198 extracellular matrix organization
GO:0043206 extracellular fibril organization
GO:0048251 elastic fiber assembly
GO:0071493 cellular response to UV-B
Cellular Component
GO:0001527 microfibril
GO:0005576 extracellular region
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
GO:0071953 elastic fiber
Protein Structure and Domains
PDB ID
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
PFAM PF00147
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55083
PhosphoSite PhosphoSite-P55083
TrEMBL
UniProt Splice Variant
Entrez Gene 4239
UniGene Hs.706535
RefSeq NP_002395
HUGO HGNC:7035
OMIM 600596
CCDS CCDS11208
HPRD 02789
IMGT
EMBL AC124066 AK293056 AK304528 BC062415 CH471212 L38486
GenPept AAB00968 AAH62415 BAF85745 BAG65329 EAW50888 EAW50889

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca