Version 5.4
Homo sapiens Protein: CDHR3
Summary
InnateDB Protein IDBP-35170.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDHR3
Protein Name cadherin-related family member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000325954
InnateDB Gene IDBG-35168 (CDHR3)
Protein Structure
UniProt Annotation
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR015919 Cadherin-like
PFAM PF00028
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZTQ4
PhosphoSite PhosphoSite-Q6ZTQ4
TrEMBL E7EQG5
UniProt Splice Variant
Entrez Gene 222256
UniGene Hs.729848
RefSeq NP_689963
HUGO HGNC:26308
OMIM 615610
CCDS CCDS47684
HPRD 08042
IMGT
EMBL AC004836 AC004964 AC005099 AK074414 AK126338 BC111696 BC111738 CH236947
GenPept AAI11697 AAI11739 BAB85073 BAC86529 EAL24403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca