Version 5.4
Homo sapiens Protein: GPR22
Summary
InnateDB Protein IDBP-35552.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR22
Protein Name G protein-coupled receptor 22
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000302676
InnateDB Gene IDBG-35550 (GPR22)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity In the brain regions frontal cortex, caudate, putamen and thalamus; not in pons, hypothalamus and hippocampus.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99680
PhosphoSite PhosphoSite-Q99680
TrEMBL Q59G39
UniProt Splice Variant
Entrez Gene 2845
UniGene Hs.657277
RefSeq NP_005286
HUGO HGNC:4477
OMIM 601910
CCDS CCDS5744
HPRD 03552
IMGT
EMBL AB209270 AC002381 CH236947 CH471070 HQ995527 U66581
GenPept AAB63815 AAC51304 ADZ31972 BAD92507 EAL24394 EAW83398

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca