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InnateDB Protein
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IDBP-35912.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CPAMD8
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Protein Name
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C3 and PZP-like, alpha-2-macroglobulin domain containing 8
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000291440
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InnateDB Gene
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IDBG-35910 (CPAMD8)
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Protein Structure
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| Function |
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| Subcellular Localization |
Secreted {ECO:0000305PubMed:15177561}. Cell membrane {ECO:0000269PubMed:15177561}; Peripheral membrane protein {ECO:0000269PubMed:15177561}; Extracellular side {ECO:0000269PubMed:15177561}.
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| Disease Associations |
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| Tissue Specificity |
Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. {ECO:0000269PubMed:15177561}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
3
[view]
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| Protein-Protein |
3
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0004866
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endopeptidase inhibitor activity
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GO:0004867
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serine-type endopeptidase inhibitor activity
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| Biological Process |
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GO:0010951
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negative regulation of endopeptidase activity
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR002890
Alpha-2-macroglobulin, N-terminal
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| PFAM |
PF01835
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q8IZJ3
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| PhosphoSite |
PhosphoSite-Q8IZJ3
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| TrEMBL |
F8W7D1
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| UniProt Splice Variant |
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| Entrez Gene |
27151
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| UniGene |
Hs.743609
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| RefSeq |
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| HUGO |
HGNC:23228
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| OMIM |
608841
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| CCDS |
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| HPRD |
09892
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| IMGT |
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| EMBL |
AB033109
AC008737
AC020908
AK075099
AY101765
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| GenPept |
AAM50084
BAA86597
BAC11400
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Version 5.4