InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: C2orf18

Summary

InnateDB Protein

IDBP-36020.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

C2orf18

Protein Name

chromosome 2 open reading frame 18

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000345528

InnateDB Gene

IDBG-238981 (C2orf18)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005351	sugar:proton symporter activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0008284	positive regulation of cell proliferation
GO:0008643	carbohydrate transport
GO:0055085	transmembrane transport
GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Cellular Component

GO:0000139	Golgi membrane
GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000620 Drug/metabolite transporter
IPR004853 Triose-phosphate transporter domain
IPR007271 Nucleotide-sugar transporter
IPR009262 Solute carrier family 35 member SLC35F1/F2/F6
IPR012404 Uncharacterised conserved protein UCP036436, nucleotide-sugar transporter-related
IPR013657 UAA transporter

PFAM

PF00892
PF03151
PF04142
PF06027
PF08449

PRINTS

PIRSF

PIRSF036436

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8N357