InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: USE1

Summary

InnateDB Protein

IDBP-36114.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USE1

Protein Name

unconventional SNARE in the ER 1 homolog (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000263897

InnateDB Gene

IDBG-36112 (USE1)

Protein Structure

UniProt Annotation

Function

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. {ECO:0000269PubMed:15272311}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000269PubMed:15029241}; Single-pass type IV membrane protein {ECO:0000269PubMed:15029241}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007029	endoplasmic reticulum organization
GO:0007041	lysosomal transport
GO:0015031	protein transport
GO:0030163	protein catabolic process
GO:0032940	secretion by cell
GO:0060628	regulation of ER to Golgi vesicle-mediated transport
GO:0071786	endoplasmic reticulum tubular network organization