Version 5.4
Homo sapiens Protein: PNPLA4
Summary
InnateDB Protein IDBP-361507.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNPLA4
Protein Name patatin-like phospholipase domain containing 4
Synonyms DXS1283E; GS2; iPLA2eta;
Species Homo sapiens
Ensembl Protein ENSP00000415245
InnateDB Gene IDBG-42157 (PNPLA4)
Protein Structure
UniProt Annotation
Function Lipid hydrolase.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen. {ECO:0000269PubMed:7806223}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004806 triglyceride lipase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR002641 Patatin/Phospholipase A2-related
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase
PFAM PF01734
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P41247
PhosphoSite PhosphoSite-P41247
TrEMBL C9IZF6
UniProt Splice Variant
Entrez Gene 8228
UniGene Hs.264
RefSeq NP_001135861
HUGO HGNC:24887
OMIM 300102
CCDS CCDS14129
HPRD 02112
IMGT
EMBL AC005296 AK289888 AK304586 BC020746 CH471074 U03886 U08888 U08889 U08890 U08891 U08892 U08893
GenPept AAA16491 AAA17838 AAH20746 BAF82577 BAG65374 EAW98752 EAW98753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca