Version 5.4
Homo sapiens Protein: TMEM8A
Summary
InnateDB Protein IDBP-361522.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM8A
Protein Name transmembrane protein 8A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000401338
InnateDB Gene IDBG-7505 (TMEM8A)
Protein Structure
UniProt Annotation
Function May be a cell surface adhesion molecule. May be involved in the maintenance of the resting T-cell state.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in pancreas, placenta, spleen, liver, kidney, bone marrow, peripheral blood leukocytes and tonsil. {ECO:0000269PubMed:11006113}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0008150 biological_process
Cellular Component
GO:0005765 lysosomal membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR021910 Protein of unknown function DUF3522
PFAM PF00008
PF12036
PRINTS
PIRSF
SMART SM00181
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HCN3
PhosphoSite PhosphoSite-Q9HCN3
TrEMBL K4DI83
UniProt Splice Variant
Entrez Gene 58986
UniGene Hs.288940
RefSeq NP_067082
HUGO HGNC:17205
OMIM
CCDS CCDS10407
HPRD 11636
IMGT
EMBL AB045292 AE006463 AK024725 BC004276 BC021557 CH471112 Z97634
GenPept AAH04276 AAH21557 AAK61227 BAB14975 BAB16376 CAI95598 EAW85823 EAW85824 EAW85825

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca