Version 5.4
Homo sapiens Protein: CLCN4
Summary
InnateDB Protein IDBP-361774.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLCN4
Protein Name chloride channel 4
Synonyms ClC-4; ClC-4A; CLC4;
Species Homo sapiens
Ensembl Protein ENSP00000405754
InnateDB Gene IDBG-42905 (CLCN4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005524 ATP binding
GO:0015297 antiporter activity
Biological Process
GO:0006810 transport
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
Protein Structure and Domains
PDB ID
InterPro IPR000644 CBS domain
IPR001807 Chloride channel, voltage gated
IPR002246 Chloride channel ClC-4
IPR014743 Chloride channel, core
PFAM PF00571
PF00654
PRINTS PR00762
PR01115
PIRSF
SMART SM00116
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51793
PhosphoSite PhosphoSite-P51793
TrEMBL
UniProt Splice Variant
Entrez Gene 1183
UniGene Hs.495674
RefSeq NP_001243873
HUGO HGNC:2022
OMIM 302910
CCDS CCDS59159
HPRD 02362
IMGT
EMBL AB019432 AC003666 AC121345 AF170492 AK289564 AK299611 BC130278 CH471074 X77197
GenPept AAD50981 AAI30279 BAA77327 BAF82253 BAH13080 CAA54417 EAW98778

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca