InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZFHX2

Summary

InnateDB Protein

IDBP-362411.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZFHX2

Protein Name

zinc finger homeobox 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000413418

InnateDB Gene

IDBG-3346 (ZFHX2)

Protein Structure

UniProt Annotation

Function

May be involved in transcriptional regulation.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003779	actin binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007010	cytoskeleton organization
GO:0030534	adult behavior

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001356 Homeobox domain
IPR003604 Zinc finger, U1-type
IPR007087 Zinc finger, C2H2
IPR009057 Homeodomain-like
IPR013992 Adenylate cyclase-associated CAP, N-terminal
IPR015880 Zinc finger, C2H2-like

PFAM

PF00046
PF00096
PF01213

PRINTS

PIRSF

SMART

SM00389
SM00451
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9C0A1