Version 5.4
Homo sapiens Protein: HSPH1
Summary
InnateDB Protein IDBP-363739.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPH1
Protein Name heat shock 105kDa/110kDa protein 1
Synonyms HSP105; HSP105A; HSP105B; NY-CO-25;
Species Homo sapiens
Ensembl Protein ENSP00000396090
InnateDB Gene IDBG-21616 (HSPH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 67 [view]
Protein-Protein 65 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0006986 response to unfolded protein
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0051135 positive regulation of NK T cell activation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
GO:0071682 endocytic vesicle lumen
Protein Structure and Domains
PDB ID
InterPro IPR013126 Heat shock protein 70 family
IPR029047 Heat shock protein 70kD, peptide-binding domain
IPR029048 Heat shock protein 70kD, C-terminal domain
PFAM PF00012
PRINTS PR00301
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92598
PhosphoSite PhosphoSite-Q92598
TrEMBL B4DY72
UniProt Splice Variant
Entrez Gene 10808
UniGene
RefSeq NP_001273434
HUGO HGNC:16969
OMIM 610703
CCDS CCDS73559
HPRD 09990
IMGT
EMBL AB003333 AB003334 AF039695 AK302294 AK302430 AL137142 BC037553 CH471075 D86956
GenPept AAC18044 AAH37553 BAA13192 BAA34779 BAA34780 BAG63634 BAG63733 CAI12428 CAI12429 CAI12430 EAX08479 EAX08482

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca