Version 5.4
Homo sapiens Protein: TMEM208
Summary
InnateDB Protein IDBP-36393.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM208
Protein Name transmembrane protein 208
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000305892
InnateDB Gene IDBG-36391 (TMEM208)
Protein Structure
UniProt Annotation
Function May function as a negative regulator of endoplasmic reticulum-stress induced autophagy. {ECO:0000269PubMed:23691174}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:23691174}; Multi-pass membrane protein {ECO:0000269PubMed:23691174}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006914 autophagy
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008506 Protein of unknown function DUF788, TMEM208
PFAM PF05620
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BTX3
PhosphoSite PhosphoSite-
TrEMBL J3KRY7
UniProt Splice Variant
Entrez Gene 29100
UniGene Hs.598226
RefSeq NP_054906
HUGO HGNC:25015
OMIM
CCDS CCDS45511
HPRD 13710
IMGT
EMBL AC040160 AF161519 BC003080 BC013412 BC021109 CH471092
GenPept AAF29134 AAH03080 AAH13412 AAH21109 EAW83105 EAW83106 EAW83107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca