Version 5.4
| Homo sapiens Protein: CLDN9 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-366091.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CLDN9 | ||||||||
| Protein Name | claudin 9 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000398017 | ||||||||
| InnateDB Gene | IDBG-236475 (CLDN9) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity). May act as a coreceptor for HCV entry into hepatic cells. {ECO:0000250, ECO:0000269PubMed:17804490}. | ||||||||
| Subcellular Localization | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines. {ECO:0000269PubMed:17804490}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR003553
Claudin-9 IPR004031 PMP-22/EMP/MP20/Claudin superfamily IPR006187 Claudin |
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| PFAM |
PF00822
PF13903 |
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| PRINTS |
PR01382
PR01077 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O95484 | ||||||||
| PhosphoSite | PhosphoSite-O95484 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 9080 | ||||||||
| UniGene | Hs.296949 | ||||||||
| RefSeq | NP_066192 | ||||||||
| HUGO | HGNC:2051 | ||||||||
| OMIM | 615799 | ||||||||
| CCDS | CCDS10487 | ||||||||
| HPRD | 13071 | ||||||||
| IMGT | |||||||||
| EMBL | AJ130941 BC051870 BC065830 | ||||||||
| GenPept | AAH51870 AAH65830 CAA10254 | ||||||||