InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC13A2

Summary

InnateDB Protein

IDBP-36705.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC13A2

Protein Name

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

Synonyms

NaCT; NaDC-1; NADC1; SDCT1;

Species

Homo sapiens

Ensembl Protein

ENSP00000316202

InnateDB Gene

IDBG-36703 (SLC13A2)

Protein Structure

UniProt Annotation

Function

Cotransport of sodium ions and dicarboxylates such as succinate and citrate.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0015361	low affinity sodium:dicarboxylate symporter activity

Biological Process

GO:0006810	transport
GO:0006814	sodium ion transport
GO:0006835	dicarboxylic acid transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001898 Sodium/sulphate symporter
IPR004680 Citrate transporter-like domain

PFAM

PF00939
PF03600

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13183

PhosphoSite

PhosphoSite-Q13183

TrEMBL

UniProt Splice Variant

Entrez Gene

9058

UniGene

Hs.102307

RefSeq

NP_003975

HUGO

HGNC:10917

OMIM

604148

CCDS

CCDS11231

HPRD

09164

IMGT

EMBL

AC015917 AK298388 AK314684 BC096277 BC096278 BC096279 U26209

GenPept

AAA98504 AAH96277 AAH96278 AAH96279 BAG37236 BAG60623