Version 5.4
Homo sapiens Protein: MID1IP1
Summary
InnateDB Protein IDBP-367262.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MID1IP1
Protein Name MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000416670
InnateDB Gene IDBG-56618 (MID1IP1)
Protein Structure
UniProt Annotation
Function Plays a role in the regulation of lipogenesis in liver. Up-regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. Involved in stabilization of microtubules (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with microtubules. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006629 lipid metabolic process
GO:0007026 negative regulation of microtubule depolymerization
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0046890 regulation of lipid biosynthetic process
GO:0051258 protein polymerization
GO:0051351 positive regulation of ligase activity
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR009786 Spot 14 family
PFAM PF07084
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NPA3
PhosphoSite PhosphoSite-Q9NPA3
TrEMBL
UniProt Splice Variant
Entrez Gene 58526
UniGene Hs.653545
RefSeq NP_001092261
HUGO HGNC:20715
OMIM
CCDS CCDS14249
HPRD 06732
IMGT
EMBL AJ272057 AK001248 BC008908 BC019332 BK001260 CH471141 CR457220
GenPept AAH08908 AAH19332 BAA91580 CAB89113 CAG33501 DAA01482 EAW59435 EAW59436

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca