InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD70

Summary

InnateDB Protein

IDBP-367400.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD70

Protein Name

CD70 molecule

Synonyms

CD27L; CD27LG; TNFSF7;

Species

Homo sapiens

Ensembl Protein

ENSP00000395294

InnateDB Gene

IDBG-21699 (CD70)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005164	tumor necrosis factor receptor binding
GO:0005515	protein binding

Biological Process

GO:0006955

immune response

Cellular Component

GO:0005615	extracellular space
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006052 Tumour necrosis factor domain
IPR008983 Tumour necrosis factor-like domain

PFAM

PF00229

PRINTS

PIRSF

SMART

SM00207

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

M0QZW2

UniProt Splice Variant

Entrez Gene

970

UniGene

Hs.715224

RefSeq

HUGO

HGNC:11937

OMIM

602840

CCDS

HPRD

18515

IMGT

EMBL

AC008760 AK298467

GenPept

BAG60680