InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CSRP2BP

Summary

InnateDB Protein

IDBP-367802.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CSRP2BP

Protein Name

CSRP2 binding protein

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000392318

InnateDB Gene

IDBG-56851 (CSRP2BP)

Protein Structure

UniProt Annotation

Function

Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. {ECO:0000269PubMed:19103755}.

Subcellular Localization

Nucleus. Cytoplasm. Note=Mainly nuclear.

Disease Associations

Tissue Specificity

Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008080	N-acetyltransferase activity
GO:0030274	LIM domain binding