InnateDB Protein
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IDBP-368064.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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QPCTL
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Protein Name
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glutaminyl-peptide cyclotransferase-like
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000387944
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InnateDB Gene
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IDBG-57929 (QPCTL)
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Protein Structure
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Function |
Responsible for the biosynthesis of pyroglutamyl peptides. {ECO:0000269PubMed:18486145, ECO:0000269PubMed:21288892}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000269PubMed:18486145}; Single-pass type I membrane protein {ECO:0000269PubMed:18486145}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
15
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006508
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proteolysis
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GO:0017186
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peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
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Cellular Component |
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PDB ID |
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InterPro |
IPR007484
Peptidase M28
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PFAM |
PF04389
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NXS2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54814
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UniGene |
Hs.631556
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RefSeq |
NP_001156849
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HUGO |
HGNC:25952
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OMIM |
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CCDS |
CCDS54282
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HPRD |
08612
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IMGT |
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EMBL |
AC007191
AK000091
AK172764
AK222636
BC011553
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GenPept |
AAH11553
BAA90938
BAD18747
BAD96356
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