InnateDB Protein
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IDBP-368110.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RBFOX1
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Protein Name
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RNA binding protein, fox-1 homolog (C. elegans) 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000402745
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InnateDB Gene
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IDBG-13650 (RBFOX1)
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Protein Structure
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Function |
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. {ECO:0000269PubMed:16537540}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Predominantly expressed in muscle and brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
42
[view]
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Protein-Protein |
42
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000504
RNA recognition motif domain
IPR017325
RNA binding protein Fox-1
IPR025670
Fox-1 C-terminal domain
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PFAM |
PF00076
PF12414
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PRINTS |
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PIRSF |
PIRSF037932
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NWB1
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PhosphoSite |
PhosphoSite-Q9NWB1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54715
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UniGene |
Hs.617542
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RefSeq |
NP_665899
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HUGO |
HGNC:18222
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OMIM |
605104
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CCDS |
CCDS45405
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HPRD |
16091
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IMGT |
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EMBL |
AC005774
AC006075
AC006112
AC007012
AC007217
AC007222
AC007223
AC009135
AC022206
AC023829
AC027683
AC079410
AC125796
AC131390
AF094849
AF107203
AF109106
AF109107
AF109108
AF109109
AF109110
AF109111
AF109112
AF109113
AF109114
AF109115
AF109116
AF109117
AF109118
AF109119
AF109120
AF229057
AF448859
AK001027
BC113691
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GenPept |
AAF78291
AAI13692
AAL71904
AAL83405
AAL83406
AAL83407
AAL83408
AAL83409
AAP41925
BAA91472
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