Version 5.4
Homo sapiens Protein: DEPDC1B
Summary
InnateDB Protein IDBP-368259.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEPDC1B
Protein Name DEP domain containing 1B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000389101
InnateDB Gene IDBG-22834 (DEPDC1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR000591 DEP domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PF00610
PRINTS
PIRSF
SMART SM00324
SM00049
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WUY9
PhosphoSite PhosphoSite-Q8WUY9
TrEMBL F5H072
UniProt Splice Variant
Entrez Gene 55789
UniGene Hs.743369
RefSeq NP_001138680
HUGO HGNC:24902
OMIM
CCDS CCDS47214
HPRD 16794
IMGT
EMBL AC016591 AC109133 AF303178 AF488828 AF490257 AK001166 AK002114 AK290684 AK300782 BC010904 BC019075 CH471123
GenPept AAH10904 AAH19075 AAN31126 AAO49477 AAO85465 BAA91529 BAA92089 BAF83373 BAG62446 EAW54998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca