InnateDB Protein
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IDBP-368407.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PHF11
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Protein Name
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PHD finger protein 11
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000405227
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InnateDB Gene
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IDBG-33454 (PHF11)
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Protein Structure
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Function |
Positive regulator of Th1-type cytokine gene expression. {ECO:0000269PubMed:18405956}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:18405956}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta. {ECO:0000269PubMed:18405956}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
11
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001965
Zinc finger, PHD-type
IPR011011
Zinc finger, FYVE/PHD-type
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00249
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q9UIL8
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TrEMBL |
X6RH80
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UniProt Splice Variant |
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Entrez Gene |
51131
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UniGene |
Hs.369039
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RefSeq |
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HUGO |
HGNC:17024
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OMIM |
607796
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL139321
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GenPept |
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