InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STXBP2

Summary

InnateDB Protein

IDBP-368566.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STXBP2

Protein Name

syntaxin binding protein 2

Synonyms

FHL5; Hunc18b; MUNC18-2; pp10122; UNC18-2; UNC18B;

Species

Homo sapiens

Ensembl Protein

ENSP00000413606

InnateDB Gene

IDBG-23137 (STXBP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017075	syntaxin-1 binding
GO:0030348	syntaxin-3 binding

Biological Process

GO:0001909	leukocyte mediated cytotoxicity
GO:0006887	exocytosis
GO:0006904	vesicle docking involved in exocytosis
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0043304	regulation of mast cell degranulation
GO:0043312	neutrophil degranulation

Cellular Component

GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016324	apical plasma membrane
GO:0031201	SNARE complex
GO:0042581	specific granule
GO:0042582	azurophil granule
GO:0044194	cytolytic granule
GO:0070062	extracellular vesicular exosome
GO:0070820	tertiary granule