InnateDB Protein
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IDBP-36858.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KHK
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Protein Name
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ketohexokinase (fructokinase)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000260598
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InnateDB Gene
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IDBG-36852 (KHK)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
Fructosuria (FRUCT) [MIM:229800]: Benign defect of intermediary metabolism. {ECO:0000269PubMed:7833921}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011611
Carbohydrate kinase PfkB
IPR029056
Ribokinase-like
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PFAM |
PF00294
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P50053
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PhosphoSite |
PhosphoSite-P50053
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
3795
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UniGene |
Hs.567297
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RefSeq |
NP_006479
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HUGO |
HGNC:6315
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OMIM |
614058
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CCDS |
CCDS1735
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HPRD |
11774
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IMGT |
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EMBL |
AC013403
AJ005168
BC006233
CH471053
CR456801
X78677
X78678
Y09336
Y09340
Y09341
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GenPept |
AAH06233
AAX93167
CAA06409
CAA55346
CAA55347
CAA70516
CAA70521
CAA70522
CAA70523
CAG33082
EAX00643
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