InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: POLR2B

Summary

InnateDB Protein

IDBP-368737.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

POLR2B

Protein Name

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

Synonyms

hRPB140; hsRPB2; POL2RB; RPB2;

Species

Homo sapiens

Ensembl Protein

ENSP00000391452

InnateDB Gene

IDBG-20530 (POLR2B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 94 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	94 [view]
Protein-Protein	93 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0032549	ribonucleoside binding

Biological Process

GO:0006351

transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6
IPR007641 RNA polymerase Rpb2, domain 7
IPR007642 RNA polymerase Rpb2, domain 2
IPR007644 RNA polymerase, beta subunit, protrusion
IPR007645 RNA polymerase Rpb2, domain 3
IPR007646 RNA polymerase Rpb2, domain 4
IPR007647 RNA polymerase Rpb2, domain 5

PFAM