InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZDHHC13

Summary

InnateDB Protein

IDBP-368897.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZDHHC13

Protein Name

zinc finger, DHHC-type containing 13

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000400113

InnateDB Gene

IDBG-35482 (ZDHHC13)

Protein Structure

UniProt Annotation

Function

Palmitoyltransferase for HD and GAD2. Mediates Mg(2+) transport. {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0015095	magnesium ion transmembrane transporter activity
GO:0016409	palmitoyltransferase activity
GO:0019706	protein-cysteine S-palmitoyltransferase activity

Biological Process

GO:0007165	signal transduction
GO:0008152	metabolic process
GO:0015693	magnesium ion transport
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0000139	Golgi membrane
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030660	Golgi-associated vesicle membrane
GO:0043231	intracellular membrane-bounded organelle