InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EPB41L4A

Summary

InnateDB Protein

IDBP-36907.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPB41L4A

Protein Name

erythrocyte membrane protein band 4.1 like 4A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000261486

InnateDB Gene

IDBG-36903 (EPB41L4A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in many tissues. High levels of expression in brain, liver, thymus and peripheral blood leukocytes and low levels of expression in heart, kidney, testis and colon.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0019898	extrinsic component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000299 FERM domain
IPR000798 Ezrin/radixin/moesin like
IPR014847 FERM adjacent (FA)
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain

PFAM

PF08736
PF09379
PF09380
PF00373

PRINTS

PR00661
PR00935

PIRSF

SMART

SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt