Version 5.4
Homo sapiens Protein: PAX5
Summary
InnateDB Protein IDBP-369337.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAX5
Protein Name paired box 5
Synonyms ALL3; BSAP;
Species Homo sapiens
Ensembl Protein ENSP00000404687
InnateDB Gene IDBG-65386 (PAX5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006959 humoral immune response
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0009887 organ morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001523 Paired domain
IPR009057 Homeodomain-like
IPR022130 Paired-box protein 2 C-terminal
PFAM PF00292
PF12403
PRINTS PR00027
PIRSF
SMART SM00351
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q02548
PhosphoSite PhosphoSite-Q02548
TrEMBL C0KTE3
UniProt Splice Variant
Entrez Gene 5079
UniGene Hs.619100
RefSeq NP_001267484
HUGO HGNC:8619
OMIM 167414
CCDS CCDS65041
HPRD 01334
IMGT
EMBL AF080573 AL161781 AL450267 AY463952 AY463953 AY463954 AY463955 AY463956 AY463957 CH471071 DQ841178 DQ845345 DQ845346 EF064717 FJ626408 FJ626421 FJ626422 FJ626423 FJ626424 FJ626425 M96944
GenPept AAA58397 AAC35286 AAR27590 AAR27591 AAR27592 AAR27593 AAR27594 AAR27595 ABI30005 ABI33104 ABI33105 ABK41900 ACM91591 ACM91604 ACM91605 ACM91606 ACM91607 ACM91608 CAH72137 CAH72740 EAW58294 EAW58295 EAW58296 EAW58297 EAW58298 EAW58299

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca