Homo sapiens Protein: UGT2B11
Summary
InnateDB Protein IDBP-369365.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UGT2B11
Protein Name UDP glucuronosyltransferase 2 family, polypeptide B11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387683
InnateDB Gene IDBG-238135 (UGT2B11)
Protein Structure
UniProt Annotation
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Subcellular Localization Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 0
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015020 glucuronosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0008210 estrogen metabolic process
GO:0030259 lipid glycosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235 Glycosyl transferase, family 28, C-terminal
PFAM PF00201
PF04101
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75310
PhosphoSite PhosphoSite-O75310
TrEMBL Q4W5B9
UniProt Splice Variant
Entrez Gene 10720
UniGene Hs.339811
RefSeq NP_001064
HUGO HGNC:12545
OMIM 603064
CCDS CCDS3527
HPRD 04345
IMGT
EMBL AC111000 AF016492 BC069441 BC107059 BC107060
GenPept AAC27891 AAH69441 AAI07060 AAI07061 AAY41046