InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABCC6

Summary

InnateDB Protein

IDBP-370509.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCC6

Protein Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 6

Synonyms

ABC34; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7;

Species

Homo sapiens

Ensembl Protein

ENSP00000405002

InnateDB Gene

IDBG-16763 (ABCC6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	6 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E7ESW8

UniProt Splice Variant

Entrez Gene

368

UniGene

Hs.713830

RefSeq

XP_005276105

HUGO

HGNC:57

OMIM

603234

CCDS

HPRD

04453

IMGT

EMBL

AC136624

GenPept