Version 5.4
Homo sapiens Protein: WT1
Summary
InnateDB Protein IDBP-370526.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WT1
Protein Name Wilms tumor 1
Synonyms AWT1; EWS-WT1; GUD; NPHS4; WAGR; WIT-2; WT33;
Species Homo sapiens
Ensembl Protein ENSP00000413452
InnateDB Gene IDBG-37982 (WT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 27 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000976 Wilm\'s tumour protein, N-terminal
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR017987 Wilm\'s tumour protein
PFAM PF02165
PF00096
PRINTS PR00049
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y7K5
UniProt Splice Variant
Entrez Gene 7490
UniGene Hs.606557
RefSeq NP_077742
HUGO HGNC:12796
OMIM 607102
CCDS CCDS44562
HPRD 06163
IMGT
EMBL AL049692 D13624 EF012820
GenPept ABK15552 BAF85820

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca