InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RLTPR

Summary

InnateDB Protein

IDBP-37067.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RLTPR

Protein Name

RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000334958

InnateDB Gene

IDBG-37065 (RLTPR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:19846667}. Note=Exhibits a fibrillar pattern reminiscent of intermediate filaments. Colocalizes with vimentin.

Disease Associations

Tissue Specificity

Expressed in all tissues tested, including thymus, spleen, colon, leukocytes, peripheral blood, skin, skin keratinocytes and skin fibroblasts. {ECO:0000269PubMed:15588584}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0032729	positive regulation of interferon-gamma production
GO:0042102	positive regulation of T cell proliferation
GO:0045184	establishment of protein localization
GO:0045591	positive regulation of regulatory T cell differentiation
GO:0048538	thymus development
GO:0048872	homeostasis of number of cells
GO:0050852	T cell receptor signaling pathway
GO:1900042	positive regulation of interleukin-2 secretion
GO:1902715	positive regulation of interferon-gamma secretion