InnateDB Protein
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IDBP-37073.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CHRAC1
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Protein Name
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chromatin accessibility complex 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000220913
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InnateDB Gene
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IDBG-37071 (CHRAC1)
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Protein Structure
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Function |
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
28
[view]
|
Protein-Protein |
27
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003958
Transcription factor CBF/NF-Y/archaeal histone
IPR009072
Histone-fold
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PFAM |
PF00808
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NRG0
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PhosphoSite |
PhosphoSite-Q9NRG0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54108
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UniGene |
Hs.598227
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RefSeq |
NP_059140
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HUGO |
HGNC:13544
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OMIM |
607268
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CCDS |
CCDS6379
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HPRD |
06275
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IMGT |
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EMBL |
AF226076
AK023537
BC015891
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GenPept |
AAF72416
AAH15891
BAB14601
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