InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PDHX

Summary

InnateDB Protein

IDBP-371275.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDHX

Protein Name

pyruvate dehydrogenase complex, component X

Synonyms

DLDBP; E3BP; OPDX; PDX1; proX;

Species

Homo sapiens

Ensembl Protein

ENSP00000389404

InnateDB Gene

IDBG-39515 (PDHX)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016746	transferase activity, transferring acyl groups

Biological Process

GO:0006090	pyruvate metabolic process
GO:0008152	metabolic process
GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044237	cellular metabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005759

mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000089 Biotin/lipoyl attachment
IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain
IPR004167 E3 binding
IPR011053 Single hybrid motif

PFAM

PF00364
PF00198
PF02817

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O00330

PhosphoSite