InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DAXX

Summary

InnateDB Protein

IDBP-371714.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DAXX

Protein Name

death-domain associated protein

Synonyms

BING2; DAP6; EAP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000396876

InnateDB Gene

IDBG-82726 (DAXX)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 177 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	177 [view]
Protein-Protein	174 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0003714	transcription corepressor activity
GO:0005057	receptor signaling protein activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0019899	enzyme binding
GO:0019901	protein kinase binding
GO:0030295	protein kinase activator activity
GO:0031072	heat shock protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0042393	histone binding
GO:0042803	protein homodimerization activity
GO:0047485	protein N-terminus binding
GO:0050681	androgen receptor binding

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0006334	nucleosome assembly
GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0007257	activation of JUN kinase activity
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
GO:0016032	viral process
GO:0030521	androgen receptor signaling pathway
GO:0031396	regulation of protein ubiquitination
GO:0045860	positive regulation of protein kinase activity
GO:0045892	negative regulation of transcription, DNA-templated
GO:1901216	positive regulation of neuron death

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016605	PML body
GO:0070603	SWI/SNF superfamily-type complex