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InnateDB Protein
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IDBP-371756.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FBXO42
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Protein Name
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F-box protein 42
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000412416
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InnateDB Gene
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IDBG-91459 (FBXO42)
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Protein Structure
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| Function |
Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. {ECO:0000269PubMed:19509332}.
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
10
[view]
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| Protein-Protein |
10
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q6P3S6
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| TrEMBL |
X6RKU3
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| UniProt Splice Variant |
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| Entrez Gene |
54455
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| UniGene |
Hs.642443
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| RefSeq |
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| HUGO |
HGNC:29249
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| OMIM |
609109
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL109627
AL358794
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| GenPept |
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Version 5.4